Clinical and Histological Evaluations of a 1060nm Laser Device for Non-Invasive Fat Reduction
JOHN W. DECORATO, MD, FACS
- 17 subjects in total were treated; 11 treatments being in the abdomen and 6 in the ank.
- Pre- and post-treatment, a thermocouple needle was placed into the treatment area to measure tissue temp at interval depths (5, 10, 15, 20, 25, 30mm).
- 1060nm diode laser with contact cooling for skin protection to cause injury to subcutaneous adipose tissue (SAT) by establishing a controlled hyperthermic temperature of 42-47°C.
• Ultrasound measurements of fat thickness were performed at baseline, 6 and 12 weeks post-treatment.
• High resolution photographs were taken at baseline and 12 weeks post-treatment.
• Laser treatments were well-tolerated by all subjects with no damage to the skin.
• Side effects included mild pain, stinging and numbness, all resolved by 2 weeks.
- Ultrasound, MRI, and photographic evaluations show similar level of fat reduction by laser hyperthermic treatment as compared to cryolipolysis (24%).
- The in vivo tissue response demonstrated that a prolonged hyperthermic exposure can cause adipocyte injury.
Fat thickness changes demonstrated by ultrasound
Baseline 3 Month Post Tx 6 Month Post Tx
Total depth of adipose tissue (cm)
Average reduction in fat volume as compared to cryolipolysis:
3 MONTH POST TX
6 MONTH POST TX
Fat Volume Reduction
Example of fat thickness changes demonstrated by MRI:
Control Side Laser Tx Control Side Laser Tx
Baseline 3 Month Post Tx
6 Month Post Tx
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