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Before and after image comparing cellulite reduction results from Day 1 to Day 71.

What Exactly is Cellulite?

Cellulite most frequently occurs around the thighs and buttocks of women. Fibrous bands of collagen called septae run vertically between the surface of the skin and the underlying tissues of the fascia. Cellulite occurs when septae are not long enough, pulling the skin down in dimples. Fat cells meant to cushion the buttocks and thighs bulge between the septae, creating a “quilted” effect. Because cellulite fat is not fuel the body can burn, it cannot be reduced through diet and exercise, making it particularly insidious.

How Does Qwo® Work?

Now there’s QWO®, the first and only FDA-approved injectable treatment for cellulite that actually works. Creams and lotions promise results, but if they work, they’re typically temporary and subtle enough that results are hardly noticeable. QWO® introduces an enzyme, collagenase, into cellulite, which targets types 1 and 3 collagen fibers that make up septae. QWO® dissolves these fibers, releasing the skin from the bridge of tissue that pulls it too tight and causes the dimpling.

QWO® is the first treatment of its kind. Previous dermatological cellulite treatments were more invasive than many patients felt comfortable undergoing. As an injectable, QWO® is the first minimally-invasive treatment that doesn’t involve significant recovery time.

Infographic titled ‘Meet Qwo’ explaining how Qwo collagenase clostridium histolyticum-aaes works to treat cellulite, with step-by-step visuals showing fibrous bands, enzyme injection, collagen breakdown, and skin smoothing.
Smiling blonde woman with smooth skin touching her face against a peach background.

Am I a Good Candidate?

In clinical trials, 30% of the women participating were purposefully chosen with Fitzpatrick skin types classified as IV, V, and VI, which means women of all ethnicities, ages, skin colors, and body types are candidates for QWO® Nearly all women get cellulite in the buttocks, so if you’re self-conscious of the dimpling of your skin, want to look better in a bathing suit, and have been waiting for a truly effective cellulite treatment, QWO® may be right for you.

What is the Treatment and Recovery Like?

Your Manhattan Aesthetics injection specialist can administer QWO® with as much ease and expertise as we do Botox® or dermal fillers. Many patients even report QWO® is a less painful injection than Botox®. After your skin is marked for ideal injection placement, QWO® is administered and the collagenase gets to work while you return to your regular daily routine. The entire treatment takes about 30 minutes.

As with any injectable aesthetic treatment, injection site tenderness, bruising, and swelling are possible, and studies show it can last up to two weeks. QWO® works best after 3 sessions scheduled 3-4 weeks apart.

Woman measuring her waist and hips with a pink measuring tape, showcasing a slim body shape in white activewear.

Consultations are Available Now

Our expert providers here at Manhattan Aesthetics would be happy to meet with you for an in-person consultation.

Simply fill out the form on this page, and one of our trusted staff members will reach out to you promptly to schedule your consultation.

Request a Consultation
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What Results Will I See?*

Initial studies have shown QWO® reduces the appearance of cellulite for even severe cases, and does so for years. You can expect improvement as early as 3 weeks from your first injections.

At Manhattan Aesthetics, we’re committed to providing our patients with the highest caliber of treatments that get results. It’s why we’re often the first in New York to introduce new technologies and medicines. QWO® is yet another example of that. It’s cutting-edge cellulite treatment without the cutting.

Close-up before treatment image showing cellulite on the buttocks (Day 1).
QWO® Before
Close-up after treatment image showing reduced cellulite on the buttocks (Day 71).
QWO® After

What Our Clients Are Saying

*Individual results may vary.

Take the Next Step – Request a Consultation

The first step is to come in for an in-person consultation with our expert providers at Manhattan Aesthetics serving Queens, Brooklyn, and the Bronx, New York, and New Jersey. Please fill out the form on this page or call our office during normal business hours at 212-960-8172.

*Individual results may vary.

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